This webcast is on heart disease caused by rheumatic fever and the reason behind the increase of this disease today or why it not analysed properly in earlier times. Further, we get to know in the first attack of rheumatic fever, how many end up with mitral stenosis, and how many can recover from it, when to intervene in the patients of confirmed rheumatic disease and how long such patients should be given penicillin prophylaxis and if the patient is of sensitive nature or penicillin is not available what other drugs can be given to them. It also explains what are the indications of mitral valve replacement, which anticoagulants should be given to such patients , and at what time it should be given during pregnancy weeks.