Pandemic policy interventions, such as the timing of vaccine boosters, take into account the length and efficiency of protection from infection with and immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The threshold for preventing a symptomatic SARS-CoV-2 infection may be lower than the threshold for preventing all infections. Vaccination has been demonstrated to provide longer-lasting protection against hospitalization and mortality than it does against symptomatic and asymptomatic illness, according to recent studies.