Modern SUs can be considered a panacea in DM care with their beneficial extra-pancreatic, pleiotropic, and cardiovascular effects. Sulfonylureas also exhibit certain endocrine and metabolic effects, which could be considered beneficial in the management of DM. Additionally, Safe glycemic control with SUs could be achieved. But, what are the factors that affect the drug and dosage selection? Is it beneficial in comparison to the other drugs in the market with a similar profile? Why sulfonylureas? Let's understand these facts in this session of a webcast titled," unravel the relevance of low dose modern SU in new age".